transition mutations造句
例句與造句
- The presence of nitrous acid can cause transition mutations, by converting cytosine to uracil.
- This results in a change in one base pair of DNA, specifically a transition mutation.
- G : U and G : T mismatches, upon DNA replication, give rise to C to T transition mutations.
- This conversion of a DNA base from cytosine ( C ) to thymine ( T ) can result in a transition mutation.
- The most frequent mutations due to inaccurate synthesis past CPDs are cytosine to thymine ( C > T ) or CC > TT transition mutations.
- It's difficult to find transition mutations in a sentence. 用transition mutations造句挺難的
- "' Ethyl methanesulfonate "'( EMS ) is a mutagenic, teratogenic, and possibly carcinogenic organic compound with transition mutation ).
- NMU is an alkylating agent, and exhibits its toxicity by transferring its methyl group to nucleobases in nucleic acids, which can lead to AT : GC transition mutations.
- "' 5-Hydroxycytosine "'is an oxidized form of cytosine that is associated with an increased frequency of C to T transition mutations, with some C to G transversions.
- One G-to-A transition mutation in codon 78 produced a truncated protein product, while mutations at codons 89 and 90 may have disrupted the active site and resulted in an inactive protein product.
- Mutations have been identified in multiple domains, although there seems to be a recurrent transition mutation ( G > A causing E1021K ) in the C lobe of the kinase domain, leading to constitutive activation of enzyme function.
- It acts by adding alkyl groups to the O 6 of guanine and O 4 of thymine, which can lead to transition mutations between GC and AT . These changes do not cause a heavy distortion in the double helix of DNA and thus are hard to detect by the DNA mismatch repair system.
- RIP occurs during the sexual stage in repeat sequences of at least 400 base pairs in length are vulnerable to RIP . Repeats with as low as 80 % nucleotide identity may also be subject to RIP . Though the exact mechanism of repeat recognition and mutagenesis are poorly understood, RIP results in repeated sequences undergoing multiple transition mutations.
- However, that said, it is known that small RNAs like miRNA can influence chromatin configuration, which can influence DNA methylation, and that DNA methylation can cause transition mutations, C to T, G to A; and the GC content of DNA is in fact far from random, e . g . at CpG islands.