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transition mutations造句

"transition mutations"是什么意思   

例句與造句

  1. The presence of nitrous acid can cause transition mutations, by converting cytosine to uracil.
  2. This results in a change in one base pair of DNA, specifically a transition mutation.
  3. G : U and G : T mismatches, upon DNA replication, give rise to C to T transition mutations.
  4. This conversion of a DNA base from cytosine ( C ) to thymine ( T ) can result in a transition mutation.
  5. The most frequent mutations due to inaccurate synthesis past CPDs are cytosine to thymine ( C > T ) or CC > TT transition mutations.
  6. It's difficult to find transition mutations in a sentence. 用transition mutations造句挺難的
  7. "' Ethyl methanesulfonate "'( EMS ) is a mutagenic, teratogenic, and possibly carcinogenic organic compound with transition mutation ).
  8. NMU is an alkylating agent, and exhibits its toxicity by transferring its methyl group to nucleobases in nucleic acids, which can lead to AT : GC transition mutations.
  9. "' 5-Hydroxycytosine "'is an oxidized form of cytosine that is associated with an increased frequency of C to T transition mutations, with some C to G transversions.
  10. One G-to-A transition mutation in codon 78 produced a truncated protein product, while mutations at codons 89 and 90 may have disrupted the active site and resulted in an inactive protein product.
  11. Mutations have been identified in multiple domains, although there seems to be a recurrent transition mutation ( G > A causing E1021K ) in the C lobe of the kinase domain, leading to constitutive activation of enzyme function.
  12. It acts by adding alkyl groups to the O 6 of guanine and O 4 of thymine, which can lead to transition mutations between GC and AT . These changes do not cause a heavy distortion in the double helix of DNA and thus are hard to detect by the DNA mismatch repair system.
  13. RIP occurs during the sexual stage in repeat sequences of at least 400 base pairs in length are vulnerable to RIP . Repeats with as low as 80 % nucleotide identity may also be subject to RIP . Though the exact mechanism of repeat recognition and mutagenesis are poorly understood, RIP results in repeated sequences undergoing multiple transition mutations.
  14. However, that said, it is known that small RNAs like miRNA can influence chromatin configuration, which can influence DNA methylation, and that DNA methylation can cause transition mutations, C to T, G to A; and the GC content of DNA is in fact far from random, e . g . at CpG islands.

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